The invention relates to the technical field of ink, and in particular relates to a production method of white lithographic ink, which comprises the following steps of: (1) wetting titanium pigment with water; (2) adding base materials; (3) stirring for the second time; (4) dewatering; (5) grinding; (6) adding additives; and (7) adjusting the viscosity. According to the production method of the white lithographic ink, the titanium pigment is wet by water firstly, the water has low surface tension, and the titanium pigment has good hydrophily, so that water easily replaces the air in the gaps of the titanium pigment so as to realize the aim of wetting the titanium pigment; then alcoholic varnish is used for replacing the water to achieve good wetting effect on the titanium pigment, so that the production time of the subsequent grinding process can be further shortened, therefore, the production method of the white lithographic ink can greatly shorten the grinding time of the subsequent grinding process, thereby improving production efficiency.