The invention discloses a weeding composition containing cyhalofop-butyl and prosulfocarb. The weeding composition takes the cyhalofop-butyl and the prosulfocarb as effective components, and the mass ratio of the cyhalofop-butyl to the prosulfocarb is 1: (11 to 52). The weeding composition has strong complementarity, and obvious synergism, can effectively prevent and weed weeds of the grass family, weeds of the sedge family, and broadleaf weeds in a paddy field, overcome the defects of weed spectrum of formulation with single active ingredient, namely the prosulfocarb and the cyhalofop-butyl, and solve the problem of grass disaster in the paddy field.