The invention discloses a multilayered composite sleeve. The structure of the multilayered composite sleeve is columnar, and the cross section of the multilayered composite sleeve is ring-shaped. The multilayered composite sleeve sequentially comprises an outer layer, a filling layer, a framework layer, a buffering layer and an inner framework layer from outside to inside, wherein the outer layer is a thermoplastic material or hard rubber; the filling layer is a polyurethane or rubber hard foaming layer; the framework layer and the inner framework layer are made of glass fiber resin materials; and the buffering layer is soft rubber or polyurethane foaming sponge. The inner framework layer and the framework layer of the multilayered composite sleeve are made of the glass fiber resin materials, so that the whole sleeve has certain elasticity and is assembled with an inflatable mandrel conveniently, and the multilayered composite sleeve is light in weight, high in strength, and safe and reliable in a high-speed printing process; the structure of the multilayered composite sleeve is adopted, characteristics of a high polymer material are utilized and played, and the multilayered composite sleeve is in close fit with the inflatable mandrel to finish flexographic printing operation.