The invention relates to a method for leaching nickel and molybdenum from nickel-molybdenum ore, in particular to a method for decomposing the nickel-molybdenum ore with molybdophosphate heteropoly acid. According to the invention, P in phosphate anion is used as a central atom to form the molybdophosphate heteropoly acid with molybdenum in an acid solution, so as to increase the solubility in an acid solution, and improve the leaching rate of nickel and molybdenum of the nickel-molybdenum ore during acid leaching. The method has the advantages of being high in nickel and molybdenum leaching rate, short in technological process, simple in equipment, simple and convenient to operate, low in production cost, environment-friendly and the like, and is convenient for large-scale industrial application.