The invention discloses a curtain wall with a vertical aluminum sealing edge and relates to the technical field of constructional engineering. The curtain wall with the vertical aluminum sealing edge comprises an auxiliary glass frame, a front-face curtain wall plate and a frame-shaped aluminum alloy section, wherein the frame-shaped aluminum alloy section is positioned on the side face of the front-face curtain wall plate. The curtain wall with the vertical aluminum sealing edge comprises a first bent connecting portion and a second bent connecting portion, the first bent connecting portion and the front-face curtain wall plate are fixed through a section positioning part and a fastener, a press plate of the auxiliary glass frame and the second bent connecting portion which is a U-shaped groove are fixed through fasteners, a connecting position is positioned at the bottom of the U-shaped groove, a cover plate is arranged at an opening position of the U-shaped groove, and a rubber strip notch for mounting a sealing rubber strip is formed in the end of the frame-shaped aluminum alloy section or the press plate of the auxiliary glass frame. The curtain wall with the vertical aluminum sealing edge is capable of constructing an integral jointless side sealing edge, avoiding of blocking an opening by a sealant and meeting the visual requirement on distinct edges and corners.