The invention discloses an integrated intelligent gateway machine configuration method based on unified modeling of a transformer station. The method comprises the following steps: performing the unified modeling on IEDs at a transformer station layer in advance; introducing manufacturer initial model files of all the IEDs of the transformer station; carrying out static inspection; generating SCD/SSD engineering files of unified data structures, shared by all the IEDs; when file data needs to be downloaded for specific station control layer devices, downloading the file data for specific IED devices by use of a corresponding download approach; and when databases and figure files need to be configured to the station control layer devices, based on the SCD/SSD engineering files of the unified data structure, shared by all the IED devices, configuring the needed databases and figure files for the station control layer devices by use of a unified modeling language (UML). The method provided by the invention can reduce data check work of each intelligent device, improves the intelligent debug, design and operation efficiency, effectively improves the power supply quality of the transformer station and also has the advantages of good versatility, high practicality and convenient application.