The invention discloses a method for promoting enzymatic hydrolysis of lignocellulose. The method comprises the following steps: (1) mixing lignocellulose and a pH regulation solution for obtaining a first liquid-solid mixture, wherein the lignocellulose is subjected to pretreatment in advance, and the pH value of the pH regulation solution is 4.0-10.0; (2) adding a metal salt solution to the first liquid-solid mixture, and reacting for preset time to obtain a second liquid-solid mixture; (3) separating the second liquid-solid mixture to obtain a solid; and (4) enabling the solid to be subjected to enzymatic hydrolysis by utilizing cellulose. With the adoption of the method, the invalid adsorption of lignin for the cellulose can be effectively reduced, the enzymatic hydrolysis of the lignocellulose is promoted, and the saccharifying efficiency of the cellulose is improved; and the method is low in cost, and easy for popularization and use.