The invention discloses a horizontal well up-going fracturing method for screen pipe suspension well completion. Firstly, a bridge plug is put in a shaft to block the lower space of a horizontal casing pipe. Then, the pipe wall of the horizontal casing pipe is perforated, and thus a cement extruding channel is provided by an engineering hole in the pipe wall of the horizontal casing pipe. Afterwards, cement is extruded into the engineering hole to block the annular space between the horizontal casing pipe and the well wall, and then a target-layer well section can be perforated and fractured. In the process, a cement ring formed by cement setting can block the lower space of the annular space, the effect that fracturing fluid cannot move downwards into a horizontal production section in the fracturing process of the target-layer well section is guaranteed, and thus the problem that an up-going layer well section in a well section below a suspender and above a horizontal production section cannot be fractured in the prior art is solved, and normal proceeding of horizontal well up-going fracturing for screen pipe suspension well completion is guaranteed.