The invention discloses an ankle joint sprain treatment device which comprises a first lifting rod, a second lifting rod, a supporting plate, a rotary plate, an inflation pad and an inflation sleeve, wherein the inflation pad is located on the rotary plate, and the two ends of the inflation sleeve are open. One end of the supporting plate is movably connected with one end of the rotary plate, the rotary plate can rotate around the end, the other end of the rotary plate is fixedly connected with one end of the first lifting rod, the other end of the supporting plate is fixedly connected with one end of the second lifting rod, and the second lifting rod is inserted from the other end of the first lifting rod and can slide in the first lifting rod. The ankle joint sprain treatment device solves the problem that a cold compress, lifting and pressurizing method is single, and is reasonable and compact in structure and convenient to use. An injured ankle joint can be locally cooled through an ice belt, and inflammatory response is inhibited. By means of the inflation sleeve and a lifting adjusting mechanism, pressure can be applied to affected limbs, the affected limbs can be lifted, and the injured joint is protected against bleeding and edema.