The invention discloses a traditional Chinese medicine preparation for treating chronic amebic dysentery. The traditional Chinese medicine preparation comprises 15-25 g of Chinese pulsatilla roots, 5-15 g of brucea javanica, 10-20 g of scutellaria baicalensis, 10-20 g of coptis chinensis, 10-20 g of cortex magnoliae officinalis, 10-20 g of agastache rugosa, 10-20 g of cyrtomium fortune, 5-8 g of dried lonicera japonica thunb, 5-8 g of radix puerariae, 5-15 g of radix sanguisorbae, 5-10 g of pinellia ternata, 10-15 g of radix paeoniae alba, 10-15 g of mangnolia officinalis, 10-15 g of rosa banksiae, 10-15 g of atractylodes macrocephala, 5-10 g of dried ginger and 5-10 g of areca catechu. The traditional Chinese medicine preparation disclosed by the invention has a pure traditional Chinese medicine formula, is definite in diagnosis, and has the effects of strengthening body resistance and eliminating evil, enriching qi and nourishing blood as well as nourishing yin and strengthening intestines, medicines can directly act the focus, growth of histolytic ameba can be inhibited, functions of converging, diminishing inflammation and relieving pain of intestinal mucosa can be achieved, advantages of removing toxin and drying dampness, killing insect and relieving dysentery as well as raising yang and checking diarrhea can be brought into play, immunity of the organism can be improved, and a very good treatment effect on chronic amebic dysentery can be achieved.