The invention discloses a method for determining trace elements and heavy metals in a Centropus sinensis medicinal material. Atomic absorption and atomic fluorescence method are used for determining contents of trace elements and heavy metals in the Centropus sinensis medicinal material to be measured after processing. The research shows that Centropus sinensis medicinal materials from different producing areas are rich in trace elements and have high medicinal values; but detection rate of heavy metals is high, and a certain risk coefficient exists in quality safety of medicinal materials. The method is used for testing quality of the Centropus sinensis medicinal materials from different producing areas, providing a scientific basis for evaluation of quality of the Centropus sinensis medicinal materials, and guarantying quality of the Centropus sinensis medicinal materials.