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CN105555945B 平面膜片钳装置以及平面膜片钳系统 有权

平面膜片钳装置以及平面膜片钳系统
摘要：
一种平面膜片钳装置，具有：电绝缘性基板(2)，其在细胞配置区域(4)内具有不使细胞通过但能够使液体通过的贯通孔(3)；第一贮液部(6)，其以能够与贯通孔(3)连通的方式设置在基板(2)的第一表面(2S)侧，且保持第一导电性液体；第一电极部(7)，其配置为能够与第一贮液部(6)电导通；第二贮液部(6′)，其以能够与贯通孔(3)连通的方式设置在基板(2)的第二表面(2S′)侧，且保持第二导电性液体；第二电极部(7′)，其配置为能够与第二贮液部(6′)电导通；送液流路(8)，其向第二贮液部(6′)输送第二导电性液体；排液流路(9)，其从第二贮液部(6′)排出第二导电性液体；以及阀(10)，其设置于送液流路(8)以及/或者排液流路(9)，能够允许或者停止第二导电性液体的流通，并且能够允许或者停止第二贮液部(6′)与第二电极部(7′)的电导通。
摘要（英）：

A planar patch clamp device comprising: an electrical insulating substrate (2) having a first surface having a cell arrangement region and a second surface of the opposite surface and having a through hole (3) in the cell arrangement region which does not pass cells, but pass liquid; a first reservoir (6) provided at the first surface side (2S) of the electrical insulating substrate (2) to be able to communicate with the through hole (3) and hold a first conductive liquid; a first electrode part (7) arranged to be able to be electrically conductive with the first reservoir (6) through the first conductive liquid; a second reservoir (6') provided at the second surface side (2S') of the electrical insulating substrate to be able to communicate with the through hole (3) and hold a second conductive liquid; a second electrode part (7') arranged to be able to be electrically conductive with the second reservoir (6') through the second conductive liquid; a supply path (8) connected to the second reservoir (6') and supplying the second conductive liquid to the second reservoir; a discharge path (9) connected to the second reservoir and discharging the second conductive liquid from the second reservoir (6'); and a valve (10) provided in the supply path and/or discharge path, able to allow or stop the flow of the second conductive liquid, and also able to allow or stop electrical conduction between the second reservoir (6') and the second electrode part (7').

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