The present invention discloses a titanium dioxide production process calcining tail gas processing method comprising the following steps: 1) dust removal; 2) preliminary heat exchange, to be more specific, calcining tail gas after the dust removal is discharged into a waste heat boiler system for heat exchange with process water, and the calcining tail gas is preliminarily calcined; 3) further heat exchange, to be more specific, the preliminarily-calcined calcining tail gas enters a venturi system and further cooled by spraying with spent sulfuric acid; and 4) desulfurization. According to the titanium dioxide production process calcining tail gas processing method, waste heat boiler system with high heat recovery utilization rate is used, and by step-by-step heat exchange, heat can be efficiently recovered from the calcining tail gas, and can be used for other processes in a titanium dioxide production line, energy and water consumption can be greatly saved, and by the desulfurization, desulfurization rate of the calcining tail gas is significantly increased.