The invention relates to a method for measuring the content and distribution of elements in lead fluoride crystals. The method is used for analyzing the content and distribution of the elements in the lead fluoride crystals by taking a tablet prepared from lead oxide powder and a standard solution as a solid standard reference substance and taking 206Pb in the lead oxide powder as an internal standard element according to a laser corrosion inductance coupling plasma mass spectroscopy. By the adoption of a simple and quick standard sample preparation method, a solid reference substance with stable performance and high uniformity is obtained, and an obtained standard curve is higher in linear relevance, so that a high-purity lead fluoride sample can be quantitatively researched in a distributed manner. The method disclosed by the invention can be directly used for solid sample injection analysis without pre-treatment or preparation of a solid into a solution, and the distribution situation of the elements on the surfaces of the crystals can be also obtained.