The invention discloses an array substrate and a driving method thereof and related devices. The array substrate comprises multiple pixel units which are arranged in arrays, and data lines and gate lines. Each pixel unit comprises a driving module which is connected with the data lines and the gate lines and a light-emitting device which is connected with the driving module. Every two adjacent columns of pixel units act as a pixel group, two columns of pixel units in each pixel group share one data line, and one gate line is arranged between two adjacent rows of pixel units. The polarity of driving voltage of the driving modules in the two pixel units driven by the same gate line in the same pixel group is opposite. The polarity of driving voltage of the driving modules in the two pixel units driven by the same gate line in the same pixel group is opposite so that the two driving modules can be controlled to alternately work by one data line, and thus the number of the data lines can be reduced without increasing the number of row scanning data lines.