The embodiment of the invention discloses a method and a device for controlling the restart of loudspeaker boxes, a mobile terminal, a loudspeaker box and a system. The method comprises the steps of acquiring a restart command which acts on the mobile terminal and is used for restarting at least two loudspeaker boxes to be restarted in a wireless mesh network; and sending the restart command to a current main loudspeaker box in the wireless mesh network, thus allowing the current main loudspeaker box to restart the at least two loudspeaker boxes to be restarted according to the restart command. According to the method provided by the invention, the technical problem that in the prior art, the restart efficiency of the loudspeaker boxes is low due to the fact that only one loudspeaker box can be controlled for restarting and each loudspeaker box needs to be restarted respectively when a plurality of loudspeaker boxes needs to be restarted is solved, the existing loudspeaker box restart control technologies are optimized, and the individual and convenient control requirement on the restart of the loudspeakers is met.