The invention discloses a technology and a device for degrading industrial organic exhaust gas through collaboration of low-temperature plasma with two-stage catalysis. The device comprises a plasma catalytic reactor and a catalytic reactor which are connected sequentially, wherein the plasma catalytic reactor comprises a first casing, an electrode pair arranged in the first casing and a first catalyst arranged between the electrode pair; the catalytic reactor comprises a second casing and a catalyst bed arranged in the second casing, and a second catalyst is arranged on the catalyst bed. With the adoption of the technology and the device, deep treatment of large-air-quantity and low-concentration industrial exhaust gas can be realized, discharge of byproducts is controlled, and the cost is low.