The invention discloses a crimping machine for a radiator water chamber. The crimping machine comprises a machine frame, a water chamber pressing die, a left die, a left die worktable, a right die, a right die worktable, a core supporting base and a PLC. The water chamber pressing die is arranged above the machine frame, the left die worktable is arranged on the left side of the machine frame, and the right die worktable is arranged on the right side of the machine frame. The left die comprises a first crimping die, a second crimping die and a left die side edge crimping die, and the left die side edge crimping die is arranged on the first crimping die. The right die comprises a third crimping die, a fourth crimping die and a right die side edge crimping die, and the right die side edge crimping die is arranged on the third crimping die. The crimping machine is easy to operate, automatic crimping of the water chamber and a core main board is controlled through a PLC system, the crimping machine can be adjusted according to the specification of a workpiece water chamber to meet crimping assembly requirements of water chambers in various specifications, assembly speed is high, and compared with manual crimping, machining efficiency is greatly improved.