The invention discloses a shake-proof and fresh-preservation method for delivering grapes by express. The method comprises the grape picking process, the packing process, the fresh-preservation process and the treatment process after express receiving. Fresh grapes which are picked early that morning and not treated with a ripening agent and is ninety-percent mature and high in quality are put into a foam box, and the foam box is filled with shake-proof filler of foam particles or popcorn each time one layer of the fresh grapes is put; the grapes and the foam box which is not covered with a cover temporarily are put into a refrigerating chamber or cabinet to be cooled; the foam box is taken out before goods delivery is conducted, a sponge is put on the foam box, and then the foam box is covered with the foam box cover, compaction is conducted to enable gaps to be not reserved in the box, the portions of the cover and the bottom are well sealed and fixed, the foam box is sleeved with a plastic bag and put into a carton, and goods delivery is conducted after an opening of the carton is sealed; a client conducts unpacking after receiving the express, the grapes and the filler are put into a water basin together, the floating-up filler is scooped up, and the rinsed and leached grapes are put into a refrigerator for preservation finally. The shake-proof and fresh-preservation method is suitable for delivering the grapes by express, it is guaranteed that grain shattering, compression, frowst and deterioration do not occur on the grapes in the express delivery process, and the grapes are kept fresh and good to the maximum extent.