The invention discloses a packaging structure and a manufacturing method for a pressure sensor. The packaging structure for the pressure sensor comprises the pressure sensor, an insulating layer, a metal convex block connected with an electrode, a packaging cavity with a cubic structure, and a conductive layer, wherein the pressure sensor comprises a pressure sensitive structure for sensing external pressure and the electrode for converting the sensed voltage information into an electric signal and leading the electric signal outwards; the pressure sensitive structure and the electrode are positioned on the first surface of the pressure sensor; the first surface of the insulating layer is in contact with the second surface of the pressure sensor; the patterned conductive layer is distributed in the perpendicular direction of the side wall panel and extends to the bottom panel; a metal wire is connected to the corresponding metal convex block through a corresponding second open pore, and is exposed through the top surface of the packaging cavity; and the pressure sensitive structure on the first surface of the pressure sensor is exposed through a first open pore.