The invention provides a real-time calling method and a related device. The real-time calling method comprises the following steps: setting a background server, wherein the background server can receive a calling request transmitted by electronic equipment of a calling party; the calling request is used for indicating a first mail account to call a second mail account; the first mail account is a mail account that is bound with the electronic equipment of the calling party, and the second mail account is a mail account that is bound with electronic equipment of an answering party; forwarding the calling request to the electronic equipment of the answering party; receiving response information transmitted by the electronic equipment of the answering party; and establishing a real-time calling connection between the electronic equipment of the calling party and the electronic equipment of the answering party. Thus when a user of the electronic equipment does not know phone numbers and social software accounts of the other party, real-time calling between the electronic equipment can be realized through the mail accounts by adopting the method provided by the embodiment of the invention.