A drive system (22) for a machine tool comprises two driving main shafts (23,24) which are at least the same in length. The two driving main shafts extend in a parallel manner and are at least the same on the torsional rigidity and axial stiffness structure. Each of the two driving main shafts is supported to rotate around a main shaft axis (25,26), and the two driving main shafts can be driven by the main shaft axes (25,26) which are coupled. Each driving main shaft (23,24) is provided with a fixed bearing (27,29), so as to act on the longitudinal direction of the driving main shaft. Main shaft nuts (42,43) arranged on the driving main shaft (23,24) can be driven in a simultaneous longitudinal moving method along the longitudinal direction of the driving main shafts (23,24). The machine tool is set to have the drive system (22) in the described type.