The invention provides a frame structure for a data machine room. The frame structure comprises multiple horizontally-arranged dimension boards, flange uprights and center column joints, wherein each dimension board comprises four steel channel beams on the four sides; the flange uprights are used for supporting the dimension boards and are hollow, the flange uprights comprise the bottom-layer flange uprights and the standard-layer flange uprights, and each standard-layer flange upright is inserted in one end of the corresponding bottom-layer flange upright from top to bottom; and each center column joint is used for connecting two corresponding steel channel beams extending in two perpendicular directions, every two steel channel beams extending in the two perpendicular directions are connected with the corresponding center column joint through bolts, and each center column joint is fixed to a first flange plate and a second flange plate through bolts. By the adoption of the frame structure, the dimension boards can be increased or decreased according to the production and use requirements, flexibility is high, and installation is quick.