The invention provides an UPFC control method based on nerve network sliding mode control, which utilizes a converter targeting a parallel connection side and a serial connection side, and, on the basis of the vector control, constructs the state space of the parallel connection side and the serial connection side of the converter, adopts the radial basic function (RBF) nerve network algorithm and the momentum factor based on the classic gradient decedent algorithm to perform regulation on the hidden layer node center, the node width and the network weight value. The UPFC control method disclosed by the invention can realize the whole process adaptive control of the sliding mode state, removes the sensitivity of the sliding mode control to the external parameters, realizes the decoupling control of the active power and the reactive power, inhibits the oscillation during the system interference, and fast approaches the object value of the system operation. The structure is simple and the operation is reliable, and has good adaptability and robustness. The invention makes up the blanket in the field and provides necessary technical support and the beneficial reference to the improvement of unifying power flow controller stable control system.