The invention relates to a reservoir stratum prediction method. The method is characterized by through carrying out intersection analysis on logging data in a research area, determining effective parameters capable of distinguishing a reservoir stratum; comprehensively using earthquake data and the logging data to carry out forward simulation on the each acquired effective parameter respectively, correspondingly carrying out characteristic response analysis and determining an optimal parameter capable of distinguishing the reservoir stratum; carrying out reservoir stratum parameter inversion on the optimal parameter, determining a reasonable reservoir stratum prediction result according to an inversion result or comparing and analyzing a forward simulation result and the inversion result and then determining a reservoir stratum prediction result. By using the method, prediction precision is increased, exploration risks are reduced and workload is decreased. The method is an effective scheme of lithologic oil and gas reservoir stratum prediction.