The invention relates to a melanin inhibitor, a skin care compound and application of the skin care compound. The melanin inhibitor is a dragon blood extract, and the dragon blood extract has an excellent tyrosinase effect and transdermal absorption and can be used as a tyrosinase inhibitor for inhibiting generation of melanin; the external skin care compound contains the dragon blood extract and an optional bamboo leaf flavone extract, and the bamboo leaf flavone extract has a good oxidation resistance effect on dragon blood and is beneficial to stability of dragon blood. After the dragon blood extract and the bamboo leaf flavone extract are compounded, a good synergistic effect can be generated, and the prepared external skin care compound obviously has a better inhibiting effect on generation of melanin than that of a single dose of the dragon blood extract. A skin care product prepared by adopting the melanin inhibitor or the external skin care compound disclosed by the invention can inhibit the tyrosine activity, reduce generation of the melanin, and effectively prevent melanin deposition and color spot generation of facial skin.