Systems and methods for analyte monitoring, particularly systems and methods for monitoring and managing life of a battery in an analyte sensor system worn by a user, are provided. Disclosed is an analyte sensor system configured to be worn by a user, comprising: an analyte sensor (312); a transceiver (316) configured to transmit and receive wireless signals; a battery (330); a battery measurement module (340) coupled to the battery and configured to measure a value indicative of a current power level of the battery; a prediction module (356) coupled to the battery measurement module and configured to predict remaining useful life of the battery based on the measured value and an assumed future usage of the analyte sensor system; and a control module (354) coupled to the transceiver and at least one of the battery measurement module and the prediction module and configured to control one or more data transmission functions of the analyte sensor system based on at least one of the measured value and the predicted remaining useful life.