The invention discloses a gingko general flavone sublingual tablet and a preparation method thereof.The sublingual tablet is prepared from, by weight, 1-260 parts of gingko general flavone, 2-25 parts of disintegrating agent and 35-245 parts of filler.Gingko general flavone is prepared from, by weight, 35-50% of quercetin, 6-16% of kaempferide and 15-25% of isorhamnetin.The gingko general flavone sublingual tablet is prepared by organically combining disintegrating agent with filler, and the tablet is put under a tongue when taken and can be rapidly disintegrated and absorbed by sublingual mucosal and directly enter blood circulation through jugular veins and superior vena cava to rapidly act so as to rapidly relieve migraine symptoms.Meanwhile, the tablet is particularly suitable for the aged and other patients having difficulty in swallowing and patients having difficulty in taking water in special environments such as battlefields, outdoor environments and tourist environments.