The invention relates to a method for treating and/or improving male erectile dysfunction by using low-intensity pulsed ultrasound. According to the method of the invention, as proved by experiments, low-intensity pulsed ultrasound therapy can repair corpus cavernosum vascular endothelial cell functions so as to promote corpus cavernosum smooth muscle cell proliferation, promote eNOS and nNOS expression, improve penile blood flow, lower a TGF-beta 1/Smad/CTGF signal pathway and reduce penile fibrosis, and thereby, improving penile pathological change and ultimately achieving erectile dysfunction treatment effects.