The invention provides an automatic locking machine and a processing method and aims at solving the problems of low processing efficiency and high labor cost in the prior art. Particularly, the automatic locking machine comprises a conveyer belt, a manipulator and a locking mechanism, wherein the conveyer belt conveys a workpiece to a first position; the manipulator moves the workpiece to a second position from a first position and moves a bearing to a preset position on the workpiece; and the locking mechanism is tightened on the workpiece at the second position and is used for fixing a screw of the bearing; and the bearing is fixed to the preset position of the workpiece to finish processing. Compared with the prior art, components capable of automatically conveying the workpiece to a working station and processing the workpiece is especially designed according to the processing requirements of the workpiece; through coordination of the components, the workpiece is firstly conveyed to the first position and then is placed at the second position for processing; meanwhile, the to-be-installed bearing is automatically placed; and then the screw is tightened, so that automatic processing is achieved; the production efficiency is improved; and the labor cost is reduced.