The invention discloses a multifunctional detachable playing multi-string lyre and aims at providing a multi-string lyre with a freely-detachable resonance chamber. The multi-string lyre comprises the resonance chamber, a lyre rod and a lyre bow. The resonance chamber is movably and fixedly provided with a fixing rack. The fixing rack is movably provided with the lyre rod. The resonance chamber is movably provided with a lyre code. Strings on the lyre rod press on the lyre code. The lyre bow is provided with bowstrings whose number corresponds to the number of the strings. One end of each bowstring is movably hooked to one end of the lyre bow. The other end of the bowstring is winded on a tightening string rotating shaft. The tightening string rotating shaft is vertically fixed to the other end of the lyre bow. In the invention, the resonance chamber is freely replaced so as to satisfy different playing needs. The multi-string lyre has abundant functions. Purchasing and maintenance cost is saved. The lyre bow has many bowstrings which can be controlled independently so that there are various kinds of playing and a harmonic effect is good.