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发明授权
CN105769382B 适合骨再生修复的生物活性多孔结构支架及其制造方法 有权 转让

适合骨再生修复的生物活性多孔结构支架及其制造方法
摘要：
本发明公开了一种适合骨再生修复的生物活性多孔结构支架，该支架包括内、外支架两部分，内支架被外支架包围，所述的内、外支架均是内部孔道结构完全贯通的多孔支架，其中所述的外支架具有高的孔隙率和高的力学强度，所述的内支架具有比外支架慢的降解速度，同时又具有高的力学强度，本发明的支架具有好的力学匹配性能，生物降解性能和骨组织修复性能，而且支架的形状，尺寸可控，孔径大小可控，支架中的内支架、外支架的材料组成和材料的分布可控。同时，本发明还提供了多孔结构支架的制造方法，该方法简单，方便，生产成本低，能够实现按骨缺损修复的需求个性化定制相应的按需求分级降解的多孔支架。
摘要（英）：

The invention discloses a biological active porous structure support suitable for bone regeneration and repair.The support comprises an inner support body and an outer support body.The inner support body is surrounded by the outer support body.The inner support body and the outer support body are both a porous support with a completely through internal channel structure.The outer support body has high porosity and high mechanical strength.The inner support body has degradation speed lower than that of the outer support body and has high mechanical strength.The support has good mechanical matching performance, biodegradability and bone tissue repair performance.The shape, the size and the aperture of the support are controllable.Material components and material distribution of the inner support body and the outer support body in the support are controllable.Meanwhile, the invention further provides a manufacturing method of the porous structure support.The method is simple, convenient to use and low in production cost, and the porous support capable of being customized according to bone defect repair and capable of being degraded stage by stage corresponding accordingly to requirements can be obtained.

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