The invention belongs to the technical field of mobile communication, and provides a channel estimation method and device of a multicast broadcast single frequency network. The method comprises following steps of carrying out reference signal related calculation, thus obtaining channel estimation values at reference signal positions; carrying out first time domain interpolation on the channel estimation values at the reference signal positions; and obtaining all channel estimation values. According to the method and the device, under a broadcast multicast channel environment, intersymbol time domain interpolation needs to be carried out by utilizing an RS (Reference Signal) spaced arrangement mode on different OFDM (Orthogonal Frequency Division Multiplexing) symbols, thus obtaining reliable channel estimation results on frequencies and overcoming estimation errors resulting from relatively high frequency fading.