The invention relates to a PAM data communication system with reflection cancellation. The present invention is directed to data communication systems and methods. More specifically, embodiments of the present invention provide a communication system that removes reflection signals. A digital data stream is processed through both tentative path and the main path. The tentative path uses a first DFE device and a reflection cancellation circuit to generate a correction signal for removing reflection signal from the digital data stream. A second DFE device removes ISI and other noises from the corrected digital data stream. There are other embodiments as well.