The invention discloses an anti-drop mobile phone, which comprises a shell body, a display screen and operation keys, wherein the display screen is arranged on the front surface of the shell body, the operation keys are arranged on the shell body and used for operating and implementing corresponding functions, and all the operation keys are arranged on the side surface of the shell body. According to the anti-drop mobile phone, function keys such as a Home key, a return key and a menu key of a mobile phone are arranged on a side surface of the mobile phone, a user can perform single-hand operation while holding the mobile phone firmly, thereby preventing the mobile phone from dropping accidentally in single-hand operating process, and achieving good operating experience. In addition, the function keys can be arranged on both side surfaces of the mobile phone, and the functions of one side surface can be selectively enabled or disabled according to the way that the user holds the mobile phone (that is, in left hand or right hand), so that the user can operate the keys conveniently when using a mobile phone with large size, thereby the user can achieve better mobile phone experience.