The invention, which belongs to the technical field of cooling of electronic equipment, discloses a two-phase flow cooling device, so that a problem that the existing two-phase flow cooling device can not be applied to cooling of small and medium-sized electronic equipment in the prior art can be solved. The two-phase flow cooling device comprises a cooling loop formed by a working medium pump, an evaporation heat exchange flow passage, a condenser and a connecting pipe. The working medium pump consists of a pump body and a drive motor; the pump body includes a pump body rotor; and the drive motor is used for driving the pump body rotor to make rotation. Besides, the two-phase flow cooling device also includes a fan; an air inlet or an air outlet of the fan is opposite to the condenser; and the fan, the pump body rotor, and a rotor of the drive motor are connected to a same rotating shaft. According to the invention, the provided two-phase flow cooling device can be applied to a small-sized or medium-sized electronic device.