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发明公开
CN105792821A 包含1-茚满硫酰胺衍生物的疼痛治疗剂和/或预防剂 有权

包含1-茚满硫酰胺衍生物的疼痛治疗剂和/或预防剂
摘要：
一种包含1?茚满硫酰胺化合物或其药学上可接受的盐的药物在小鼠热板试验以及大鼠压迫性神经损伤模型中具有镇痛效果并且因此有希望用作急性和慢性疼痛的治疗剂，该1?茚满硫酰胺化合物比如是N?[(1S)?2,2,5,7?四氟?2,3?二氢?1H?茚?1?基]硫酰胺、或N?[(1S)?2,2?二氟?7?甲基?2,3?二氢?1H?茚?1?基]硫酰胺。
摘要（英）：

A medicine comprising a 1-indansulfamide compound such as N-[(1s)-2,2,5,7-tetrafluoro-2,3-dihydro-1H-indene-1-yl]sulfamide, or N-[(1s)-2,2-difluoro-7-methyl-2,3-dihydro-1H-indene-1-yl]sulfamide, or a pharmaceutically acceptable salt thereof has an analgesic effect in the mouse hot-plate test and rat constriction nerve injury model and thus holds promise as a therapeutic agent for acute pain and chronic pain.

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