The invention discloses a high-temperature creep deformation prediction method which comprises the following steps: performing short-duration test on a target sample, introducing a comprehensive parameter Q, establishing a sigma-Q relation model, and further realizing high-temperature creep deformation prediction of the target sample. The invention provides a brand new creep deformation prediction method. According to the method, change of creep deformation of a creep experiment in the solved stress along with time nearby the known stress can be predicted by utilizing the creep experiment under a certain known stress; according to the method disclosed by the invention, prediction can be performed based on a short-duration experimental result, and the experimental time in the actual experimental process is shortened; and moreover, the problem in the prior art that the test result fluctuation is large is effectively solved, due to the method disclosed by the invention, a reasonable prediction result can be obtained under the condition that the material property dispersion is large, and the accuracy and the stability of the prediction result are improved.