The invention belongs to the field of displays and discloses a spacer, a spacer manufacturing method, a mask and a display device. The method includes: coating a photoresist material on a substrate to form a photoresist layer; using the mask for exposure of the photoresist layer, wherein the mask is provided with a pattern area and a non-pattern area, and transmittance of the pattern area is progressively increased from center to edge if the photoresist material is a negative photoresist material and is progressively decreased from center to edge if the photoresist material is a positive photoresist material; subjecting the exposed photoresist layer to development and roasting to obtain the spacer with a flat top surface. Therefore, a contact surface area of the spacer is increased, mechanical strength is enhanced, thickness uniformity of a liquid crystal box between an array substrate and a color film substrate is optimized, and display quality is improved.