The present invention provides a two-part mechano-responsive composition, comprising: Part I: a tetra-glycidyl amine multifunctional epoxy resin represented by the general formula (I); and Part II: a polythiol and an amine. The cured composition has a mechano-responsive property without adding any dyes or luminescence agents, and by subjected to mechanical stimuli, the cured composition changes its colour, and the colour is in the visible spectrum range, which can be easily checked with naked eyes; and the colour change is reversible.