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发明公开
CN105861635A 结核分枝杆菌Rv3833基因在制备治疗结核分枝杆菌潜伏感染药物中的用途 无效 - 驳回

结核分枝杆菌Rv3833基因在制备治疗结核分枝杆菌潜伏感染药物中的用途
摘要：
本发明属于生物技术领域，具体涉及结核分枝杆菌Rv3833基因在制备治疗结核分枝杆菌潜伏感染药物或制剂中的新用途。研究表明Rv3833在结核分枝杆菌进入到潜伏状态的过程当中具有重要的生物学功能，与正常生长的结核分枝杆菌相比，Rv3833基因的高表达抑制了结核分枝杆菌的生长。本发明还公开了以此基因为靶标检测潜伏期结核病的试剂盒以及以此基因构建的预防及治疗潜伏感染结核分枝杆菌的疫苗。
摘要（英）：

The invention belongs to the technical field of biology, and more specifically relates to an application of mycobacterium tuberculosis Rv3833 gene in preparation of a preparation for treating mycobacterium tuberculosis latent infection. Through research, Rv3833 has important biological function during a process that mycobacterium tuberculosis enters into a latent state, compared with the normally grown mycobacterium tuberculosis, high expression of the Rv3833 gene can inhibit the growth of mycobacterium tuberculosis. The invention also discloses a kit by taking the gene as a target for detecting tuberculosis in a latent stage and a vaccine constructed by the gene and used for preventing and treating mycobacterium tuberculosis latent infection.

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