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发明公开
CN105861670A 用于检测对黄嘌呤氧化酶抑制剂过敏性的试剂盒及方法 无效 - 驳回

用于检测对黄嘌呤氧化酶抑制剂过敏性的试剂盒及方法
摘要：
本发明涉及一种用于检测对黄嘌呤氧化酶抑制剂过敏性的试剂盒及方法。该试剂盒包括扩增引物、表面固定有捕获探针的磁性微珠及检测试剂。该用于检测对黄嘌呤氧化酶抑制剂过敏性的试剂盒和方法针对12个黄嘌呤氧化酶过敏易感的SNP位点设计特异性扩增引物和捕获探针，可分型检测12个SNP位点的型别，特异性强，且使用磁性微珠固定捕获探针，利用捕获探针与扩增产物的杂交反应进行检测，灵敏度高，能够较为快速的检测待测DNA样本中12个SNP型别。
摘要（英）：

The invention relates to a kit and a method for detecting sensitivity to a xanthine oxidase inhibitor. The kit comprises an amplification primer, a magnetic microbead and a detection reagent, wherein a capture probe is fixed on the surface of the magnetic microbead. Through the kit and the method for detecting sensitivity to the xanthine oxidase inhibitor, the specific amplification primer and the capture probe are designed according to 12 SNP sites which are highly sensitive to xanthine oxidase; the types of the 12 SNP sites can be subjected to typing detection; the specificity is high; the capture probe is fixed by the magnetic microbead; the detection is carried out by hybridization reaction of the capture probe and the amplification product; the sensitivity is high; 12 SNP types in a to-be-detected DNA sample can be relatively fast detected.

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