The present invention discloses a mine three-dimensional seismic full process geological exploration prediction method, relating to the technical field of underground coal seam exploration. The method comprises a step of using a three-dimensional seismic exploration method to delineate whether a minable coal layer bit has a concealed geological structure, a step of carrying out real-time verification and analysis evaluation on the result of three-dimensional seismic exploration with the actual roadway disclosure and drilling result as constraints, and a step of fusing the verified and analyzed minable coal layer geological information into the three-dimensional seismic exploration result, using an iterative feedback method, carrying out re-processing, re-interpretation and re-application on an exploration area result which is not in accordance with a detection precision requirement, constantly changing the constraints, and finally forming a mine three-dimensional seismic full process geological analysis result. According to the method, the accuracy of the three-dimensional seismic processing and interpretation can be effectively improved, the geological construction condition in mining influence range can be predicted and found to the maximum, the roadway mining area arrangement is facilitated, and the safety accidents can be scientifically and effectively prevented and reduced.