An aluminum-plastic film packaging method and device are provided. The method includes the steps: a to-be-hot-sealed part of an aluminum-plastic film battery is placed between an upper roller of the aluminum-plastic film packaging device and a second mold head of the aluminum-plastic film packaging device; the upper roller is mounted on the surface, directly facing to the second mold head, of a first mold head; the first mold head is capable of moving away from or close to the second die head; the first mold head is driven, so that the to-be-hot-sealed part is tightly pressed between the upper roller and the second mold head, the pre-heated upper roller is driven, and the upper roller rolls from one end of the to-be-hot-sealed part to the other end along the surface of the to-be-hot-sealed part according to a preset rail; in the upper roller rolling process, an aluminum-plastic film located below the upper roller is heated, the aluminum-plastic film is melted and combined together, and the to-be-hot-sealed part forms an aluminum-plastic film hot-sealing band consistent to the rolling rail of the upper roller, so that the aluminum-plastic film battery is packaged. With application of the method and the device, the sealing performance of the aluminum-plastic film battery is facilitated to be improved, and the reliability of aluminum-plastic film packaging is improved.