The invention discloses a processing method of laser processing equipment provided with multiple independent movement systems. The method comprises steps as follows: the multiple movement systems determine, read and process target data respectively as per predetermined rules; when the target data are processed, the movement systems continuously determine, read and process new target data as per the predetermined rules until all graphic data are processed. With the adoption of the processing method of the laser processing equipment provided with the multiple independent movement systems, the target data are read as per the predetermined rules, collisions of the multiple movement systems during processing are avoided, the multiple independent movement systems can process the different graphic data simultaneously, that is, no requirements exist for type setting rules of the processed data, and random irregular type setting can be performed, so that the utilization rate of materials is substantially increased. Meanwhile, the same design drawing document can be independently completed by the aid of multiple laser heads, so that the processing efficiency is effectively improved.