The invention provides a method for full-automatic annealing of mandrels. With the adoption of the method, the mandrels are transferred to an annealing structure in time, each mandrel is subjected to annealing operation and is transferred independently, accordingly, the full-intelligent annealing operation of each mandrel is guaranteed, the automation degree and the use efficiency of the whole equipment are improved, and harm to human bodies due to too high temperature is avoided. The method is characterized in that a mandrel of a single optical fiber perform is annealed independently, timing is performed, sensors and a manipulator are used for controlling and transferring each mandrel among three areas, namely, a to-be-annealed mandrel area, an annealing area and an annealed mandrel area, and the temperature in the annealing area is maintained to range from 950 DEG C to 1,100 DEG C.