The invention belongs to the field of biomedical materials, and particularly relates to a preparation method for hydroxyethyl cellulose hemostatic gauze. The hydroxyethyl cellulose hemostatic gauze is prepared by taking hydroxyethyl cellulose as a raw material and combining an ultrasonic processing technique with an electrospinning technique; a series of drying and sterilizing are performed, so that the hydroxyethyl cellulose hemostatic gauze is prepared. Hydroxy propyl cellulose belongs to neutral etherification products, overcomes a defect that the polar group is easy to generate a stimulation reaction to an organic body, and has the characteristics of high water swelling performance and quick hemostatic performance. The hydroxyethyl cellulose hemostatic gauze is nontoxic without stimulation, the process is simple and feasible, and the clinic application prospect is wide.