The invention discloses a glass curtain wall frame system. The glass curtain wall frame system comprises a keel framework, a mounting frame and rubber fixing strips, wherein the keel framework comprises upright columns and cross beams; the upright columns and the cross beams are fixedly connected to one another through fasteners; boss structures are arranged on the cross beams; the mounting frame is used for mounting glass plates of a glass curtain wall on the cross beams, and is arranged on the back surfaces of the glass plates; hook structures which are matched with the boss structures and are hung on the boss structures are arranged on the mounting frame; the rubber fixing strips are fixedly connected to the upright columns in space between the two adjacent glass plates in the horizontal direction; and two ends of each rubber fixing strip are respectively abutted to the two adjacent glass plates. The hook structures of the mounting frame are hung on the boss structures of the cross beams, so that the glass plates are mounted on the keel framework in a hanging manner, the glass plates are pressed and fixed by the rubber fixing strips, in disassembling and assembling processes of the glass plates, the glass plates can be disassembled by disassembling the rubber fixing strips only, time and labor are saved, and the construction period is quite easy to control.