The invention discloses an angle stop valve. The angle stop valve comprises a valve body, wherein a flowing pipeline is arranged on the valve body; the valve body and the flowing pipeline form an acute angle; a valve rod is arranged on the valve body; a rotary knob is arranged at the tail end of the valve rod; a first fixed button and a second fixed button are arranged on the rotary knob; a fine tuning rotary knob is rotatably arranged at the tail end of the rotary knob; the first fixed button and the second fixed button are used for controlling rotation and fixation of the fine tuning rotary knob; a plurality of antiskid pieces are further arranged on the fine tuning rotary knob; the included angle of the valve body and the flowing pipeline is 45 degrees; and the antiskid pieces are made of abrasion resistant rubber. According to the angle stop valve, the rotary knob is arranged at the tail end of the valve rod, the rotatable fine tuning rotary knob is further arranged on the rotary knob, during flow control, firstly, the valve rod is rotated through the rotary knob to perform coarse tuning, after the flow is adjusted to be proper, the fine tuning rotary knob is rotated to perform fine tuning, after the required flow is achieved through fine tuning, the fixed buttons are pressed for fixation, so that the adjustment accuracy of the angle stop valve is greatly improved.