The invention discloses an etching method of a laser multi-electrode packaging base. The etching method of the laser multi-electrode packaging base comprises the steps of 1, fetching preprocessed to-be-etched assemblies, coating photoresist on the surfaces of the to-be-etched assemblies, and patterning the photoresist; 2, fetching the to-be-etched assemblies processed by the step 1, placing the to-be-etched assemblies in etching liquid for wet etching; and 3, fetching and washing the to-be-etched assemblies processed by the step 2, wherein the etching liquid comprises 35-45wt% of HCL, 2-5wt% of H3PO4 and 0.05-0.2wt% of CH3COONa. The etching method for iron-cobalt-nickel alloy is provided.